Throughout the biological and biomedical sciences there is a growing need for, prescriptive ‘minimum information’ (MI) checklists specifying the key information to include when reporting experimental results are beginning to find favor with experimentalists, analysts, publishers and funders alike. Such checklists aim to ensure that methods, data, analyses and results are described to a level sufficient to support the unambiguous interpretation, sophisticated search, reanalysis and experimental corroboration and reuse of data sets, facilitating the extraction of maximum value from data sets (...) them. However, such ‘minimum information’ MI checklists are usually developed independently by groups working within representatives of particular biologically- or technologically-delineated domains. Consequently, an overview of the full range of checklists can be difficult to establish without intensive searching, and even tracking thetheir individual evolution of single checklists may be a non-trivial exercise. Checklists are also inevitably partially redundant when measured one against another, and where they overlap is far from straightforward. Furthermore, conflicts in scope and arbitrary decisions on wording and sub-structuring make integration difficult. This presents inhibit their use in combination. Overall, these issues present significant difficulties for the users of checklists, especially those in areas such as systems biology, who routinely combine information from multiple biological domains and technology platforms. To address all of the above, we present MIBBI (Minimum Information for Biological and Biomedical Investigations); a web-based communal resource for such checklists, designed to act as a ‘one-stop shop’ for those exploring the range of extant checklist projects, and to foster collaborative, integrative development and ultimately promote gradual integration of checklists. (shrink)

The purpose of the paper is to introduce a recursive model of ecological discursive sustainability, as it applies to and emerges from the history of an after-school program partnership between the School of Education at the University of Delaware, USA and the Latin American Community Center in Wilmington, Delaware, USA. This model is characterized by the development of shared ownership and collaboration between the institutional partners, the co-evolution and crossfertilization of the partners’ practices and the negotiation of institutional boundaries and (...) structures. This model was developed by analyzing dialogic discourses across six diverse ecological domains of the partnership. The purpose of the paper is to introduce a recursive model of ecological discursive sustainability, as it applies to and emerges from the history of an after-school program partnership between the School of Education at the University of Delaware and the Latin American Community Center in Wilmington, Delaware. This model is characterized by the development of shared ownership and collaboration between the institutional partners, the co-evolution and cross-fertilization of the partners' practices and the negotiation of institutional boundaries and structures. This model was developed by analyzing dialogic discourses across six diverse ecological domains of the partnership. (shrink)

Sexual hermeneutics -- Desirably queer futures -- Transcending the self -- Global conversations -- Radical sexuality and ethical responsibility -- Conclusion. How sex changes.

The success of business firms and other organizations relies on the trustworthiness of reports and other documents prepared by management accountants. This study examines the personal ethical values and ethical value types of management accountants. Data were obtained from a survey of members of the Institute of Management Accountants (IMA). The survey, composed of the Rokeach Values Survey and demographic questions, was delivered by the IMA Research Lab to membership samples. Importantly, the results indicated that the highest-ranked values were consistent (...) with values included in the IMA’s Statement of Ethical Professional Practice. That management accountants hold high ethical values better enables them to provide reliable and meaningful work to business firms and other organizations. Another important finding is that older management accountants are more concerned with moral values than their younger colleagues. This finding has notable implications for the future of the profession. (shrink)

This chapter offers a new criticism of the Mind argument that is both decisive and instructive. It introduces a plausible principle (γ) that places a requirement on one’s having a choice about an event whose causal history includes only other events. Depending on γ’s truth-value, the Mind argument fails in such a way that one or the other of the two main species of libertarianism is the best approach to the metaphysics of freedom. Libertarians argue the compatibility of freedom and (...) indeterminism, and their biggest obstacle is the Mind argument that argues an incompatibility between the two. The chapter aims to build a case for the truth of γ, and so for nonreductive libertarianism. This is achieved by defending it from the best objections that have been brought to light, thereby emphasizing γ’s prima facie plausibility. (shrink)

ABSTRACT:Biological, brain, and behavioral sciences offer strong and growing support for the virtue ethics account of moral judgment and ethical behavior in business organizations. The acquisition of moral agency in business involves the recognition, refinement, and habituation through the processes of reflexion and reflection of a moral sense encapsulated in innate modules for compassion, hierarchy, reciprocity, purity, and affiliation adaptive for communal life both in ancestral and modern environments. The genetic and neural bases of morality exist independently of institutional frameworks (...) and social structures. The latter not only shape moral behaviors within circumscribed limits, they also imply a plurality and compartmentalization of roles which may enable or impede the habituation of virtue. Becoming a virtuous agent entails the practical refinement of predispositionsin situas a member of a community of practitioners rather than entailing a normative ethical educational project seeking an intellectual resolution of abstract moral questions. (shrink)

ABSTRACT:Biological, brain, and behavioral sciences offer strong and growing support for the virtue ethics account of moral judgment and ethical behavior in business organizations. The acquisition of moral agency in business involves the recognition, refinement, and habituation through the processes of reflexion and reflection of a moral sense encapsulated in innate modules for compassion, hierarchy, reciprocity, purity, and affiliation adaptive for communal life both in ancestral and modern environments. The genetic and neural bases of morality exist independently of institutional frameworks (...) and social structures. The latter not only shape moral behaviors within circumscribed limits, they also imply a plurality and compartmentalization of roles which may enable or impede the habituation of virtue. Becoming a virtuous agent entails the practical refinement of predispositionsin situas a member of a community of practitioners rather than entailing a normative ethical educational project seeking an intellectual resolution of abstract moral questions. (shrink)

Background: Patients undergoing invasive neurosurgical procedures offer researchers unique opportunities to study the brain. Deep brain stimulation patients, for example, may participate in research during the surgical implantation of the stimulator device. Although this research raises many ethical concerns, little attention has been paid to basic studies, which offer no therapeutic benefits, and the value of patient-participant perspectives.Methods: Semi-structured interviews were conducted with fourteen individuals across two studies who participated in basic intraoperative research during their deep brain stimulator surgery. Interviews (...) explored interpretations of risks and benefits, enrollment motivations, and experiences of participating in awake brain research. Reflexive thematic analysis was conducted.Results: Seven themes were identified from participant narratives, including robust attitudes of trust, high valuations of basic science research, impacts of the surgical context, and mixed experiences of participation.Conclusion: We argue that these narratives raise the potential for a translational misconception and motivate intraoperative re-consent procedures. (shrink)

This is the first serious intellectual biography of Guy Debord, prime mover of the Situationist International and author of _The Society of the Spectacle_, perhaps the seminal book of May 1968 in France. Anselm Jappe rejects recent attempts to set Debord up as a "postmodern" icon, arguing that he was a social theorist in the Hegelian-Marxist tradition—not a precursor of Jean Baudrillard but an heir of the young Georg Lukács of _History and Class Consciousness _. Neither hagiographical nor sectarian, _Guy (...) Debord_ places its subject squarely in his historical context: the politicizing Letterist and Situationist "anti-artists" who, in the European aftermath of World War II, sought to criticize and transcend the Surrealist legacy. The book offers a lively, critical, and unusually reliable account of Debord's "last avant-garde" on its way from radical bohemianism to revolutionary theory. Jappe also discusses Debord's films, which are largely inaccessible at present. This English language edition of the book has been revised by the author and features an updated critical bibliography of Debord and the Situationists. (shrink)

For the first time, Guy Debord's pivotal work Society of the Spectacle appears in a definitive and authoritative English translation. Originally published in France in 1967, Society of the Spectacle offered a set of radically new propositions about the nature of contemporary capitalism and modern culture. At the same time it was one of the most influential theoretical works for a wide range of political and revolutionary practice in the 1960s. Today, Debord's work continues to be in the forefront of (...) debates about the fate of consumer society and the operation of modern social power. In a sweeping revision of Marxist categories, the notion of the spectacle takes the problem of the commodity from the sphere of economics to a point at which the commodity as an image dominates not only economic exchange but the primary communicative and symbolic activity of all modern societies.Guy Debord was one of the most important participants in the activities associated with the Situationist International in the 1960s. Also an artist and filmmaker, he is the author of Memoires and Commentaires sur la société du spectacle. A Swerve Edition, distributed for Zone Books. (shrink)

According to the Weak Supplementation Principle (WSP)—a widely received principle of mereology—an object with a proper part, p , has another distinct proper part that doesn't overlap p . In a recent article in this journal, Nikk Effingham and Jon Robson employ WSP in an objection to endurantism. I defend endurantism in a way that bears on mereology in general. First, I argue that denying WSP can be motivated apart from the truth of endurantism. I then go on to offer (...) an explanation of WSP's initial appeal, argue that denying WSP fails to have untoward consequences for the rest of mereology, and show that the falsity of WSP is consistent with a primary guiding thought behind it. (shrink)

Three-dimensionalists , sometimes referred to as endurantists, think that objects persist through time by being “wholly present” at every time they exist. But what is it for something to be wholly present at a time? It is surprisingly difficult to say. The threedimensionalist is free, of course, to take ‘is wholly present at’ as one of her theory’s primitives, but this is problematic for at least one reason: some philosophers claim not to understand her primitive. Clearly the three-dimensionalist would be (...) better off if she could state her theory in terms accessible to all. We think she can. What is needed is a definition of ‘is wholly present at’ that all can understand. in this paper, we offer one. (shrink)

Gilles Deleuze: Image and Text focuses on the intersection between Deleuzian philosophy and the arts.

Animal and plant species exhibit an astonishing diversity of sexual systems, including environmental and genetic determinants of sex, with the latter including genetic material in the mitochondrial genome. In several hermaphroditic plants for example, sex is determined by an interaction between mitochondrial cytoplasmic male sterility (CMS) genes and nuclear restorer genes. Specifically, CMS involves aberrant mitochondrial genes that prevent pollen development and specific nuclear genes that restore it, leading to a mixture of female (male‐sterile) and hermaphroditic individuals in the population (...) (gynodioecy). Such a mitochondrial‐nuclear sex determination system is thought to be rare outside plants. Here, we present one possible case of CMS in animals. We hypothesize that the only exception to the strict maternal mtDNA inheritance in animals, the doubly uniparental inheritance (DUI) system in bivalves, might have originated as a mitochondrial‐nuclear sex‐determination system. We document and explore similarities that exist between DUI and CMS, and we propose various ways to test our hypothesis. (shrink)

In this paper, I critically discuss one of the more influential arguments for mereological universalism, what I will call ‘the Vagueness Argument’. I argue that a premise of the Vagueness Argument is not well supported and that there are at least two good reasons for thinking that the premise in question is false.

Composite materialism, as I will understand it, is the view that human persons are composite material objects. This paper develops and investigates an argument, The Vague Singulars Argument, for the falsity of composite materialism. We shall see that cogent or not, the Vague Singulars Argument has philosophically significant ramifications.

We examine the implications of the US government’s too-big-to-fail policy as it has been applied to banks. Using alternative measures of risk, we compare the risk-taking behavior of 11 TBTF banks, identified by the Comptroller of the Currency in 1984, to a number of non-TBTF banks. We provide both theory and new empirical evidence to support our argument that the TBTF policy leads management to significantly increase risk-taking, with no corresponding increase in performance. While prior studies have considered the effects (...) of the TBTF policy on limited, but risk-related aspects of bank behavior, such as the cost of funds, our study provides direct evidence about the risk-taking behavior associated with the TBTF policy. Our study has important implications for the current political debate regarding the too-big-to-fail policy. (shrink)

Summary The positions of 129 14 to 19?year?old students on two fundamental cognitive styles dimensions (Wholist?Analytic and Verbal?Imagery) were assessed. They then received, by random allocation, one of three versions of a computer?presented instruction package on home hot water systems. The versions differed in terms of their structure (large versus small step), advance organiser (absent or present), verbal emphasis (high versus low), and diagram type (abstract versus pictorial). Version 1 had large step, no organiser, high verbal content, and abstract diagram. (...) Version 2 had small step, no organiser, low verbal content, and pictorial diagram. Version 3 was identical to Version 2, except that an organiser in the form of an elaborated introduction was given in which all five topics were introduced and each section began with an overview and ended with a summary. There was a significant interaction between version and cognitive style in their effect on recall. The results were discussed in terms of their implications for instruction. (shrink)

Immanuel Kant’s well known and thoroughly discussed criticism of the cosmological argument, hereafter ‘CA’, is that it presupposes or depends upon the cogency of the ontological argument, hereafter ‘OA’. Call this criticism ‘the Dependency Thesis’. It is fair to say that the received view on the matter is that Kant failed to establish the Dependency Thesis.1 In what follows, I argue that the received view is mistaken. I begin by rehearsing the standard objection to what is typically taken to be (...) Kant’s primary argument for the Dependency Thesis. I defend Kant by presenting a different argument for his thesis. This argument is not vulnerable to the standard objection, and there is good reason to think that Kant had such an argument in mind. (shrink)

According to perdurantism, objects persist by being spread out over time, just as composite three-dimensional objects are spread out over space. Just as a composite three-dimensional object is spread out over space by having spatial parts, objects persist, according to perdurantism, by having temporal parts. Perdurantism can be stated more precisely by saying what exactly a temporal part is. In the sequel, Theodore Sider's definition of "instantaneous temporal part" shall be assumed: x is an instantaneous temporal part of y at (...) instant t =df. x exists at, but only at, t; x is part of y at t; and x overlaps at t everything that is part of y at t. Much more could be and has been said about how perdurantism should be formulated. Though interesting in their own right, nothing of importance here turns on these matters of formulation. (shrink)

John Hawthorne’s recent monograph Knowledge and Lotteries1 is centred on the following puzzle: Suppose you claim to know that you will not be able to afford to summer in the Hamptons next year. Aware of your modest means, we believe you. But suppose you also claim to know that a ticket you recently purchased in a multi-million dollar lottery is a loser. Most of us have the intuition that you do not know that your ticket is a loser. However, your (...) alleged knowledge of not being able to afford to summer in the Hamptons puts you in a position to know that your ticket is a loser. For the proposition that you will not be able to afford to summer in the Hamptons entails the proposition that you will lose the lottery. And the following principle, what Hawthorne calls ‘Single Premise Closure’ ( p. 34), is very plausible: If you know that p, p entails q, and you competently deduce q from p thereby coming to believe that q (all the while retaining your knowledge of p), then you come to know q. (shrink)

Stephen Barker and Phil Dowe have argued, through what they call the mereological paradox, that endurantism is contradictory. In this paper, I take issue with Barker and Dowe’s argument. In addition to disarming an interesting philosophical argument against endurantism, my diagnosis of Barker and Dowe’s mereological paradox underscores what is central to the endurantism/perdurantism debate and reveals the inadequacy of a familiar way of describing enduring objects.

A theoretical framework Is presented that distinguishes among three knowledge sources that form the basis for generative performance. The three knowledge sources, termed conceptual, procedural, and utilizational competence, were implemented as a computational model that derives plans for counting procedures. In a previous analysis, Greeno, Riley, and Gelman (1984) developed a characterization of the conceptual competence (implicit understanding of general concepts and principles) associated with the skill of counting and related conceptual competence to various models of performance. In the current (...) work all three knowledge sources are formalized in a computer program (COUNTPLAN) that generates planning nets of counting procedures. The sufficiency of COUNTPLAN's knowledge components is demonstrated through its capacity to generate new plans for counting in novel settings from a core of conceptual competence. The utility of COUNTPLAN to facilitate the distinction between hypotheses of competence and hypotheses of performance is discussed. (shrink)